High morbidity and mortality in children with invasive lower respiratory tract group A streptococcal infection in England, winter 2022

Public Health 2026 Open access

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Authors: Katie Wrenn, Paula Bianca Blomquist, Carmellie Inzoungou-Massanga, Guy Rebecca, Oluwakemi Olufon, Diane Hatziioanou, Lucy Findlater, Iona Smith, Karen Luyt, Tom G. S. Williams, Sylvia Stoianova, Michelle Dickinson
+6 more Maaike E. Pietzsch, Christopher I. Jarvis, Colin Stewart Brown, Mariyam Mirfenderesky, Theresa L. Lamagni, Deepti Kumar
DOI: 10.1016/j.puhe.2026.106212
Cited by: 1
References: 12

Abstract

OBJECTIVES: To describe the epidemiological and clinical characteristics of children with invasive group A Streptococcus (iGAS) infection and severe GAS-associated lower respiratory tract infections (including empyema) [LRTIs] identified in England in late 2022, supporting earlier recognition and informing pre-hospital admission clinical decision and public health response. STUDY DESIGN: Case series analysis. METHODS: LRTI iGAS cases in children aged

Fields of Study & Subjects

Streptococcal Infections and Treatments Neonatal and Maternal Infections Pneumonia and Respiratory Infections

Publication details

Journal / source
Public Health
Publisher
Elsevier BV
Volume
253
Pages
106212–106212
Publication date
26 February 2026
Language
EN