Imaging features of an extramammary Paget’s disease of the penis: A case report and literature review

Extramammary Paget's disease is a rare cutaneous malignant neoplasm, and few studies have described its radiological features. Herein, we report the case of an 83-year-old man with extramammary Paget's disease and condyloma acuminatum. The lesion appeared cauliflower-like during a physical examination and on magnetic resonance imaging, where it exhibited a unique contrast-enhanced pattern. The superficial layer of the tumor corresponding to extramammary Paget's disease exhibited low-to-intermediate signal intensity on T1- and T2-weighted magnetic resonance images and high signal intensity on diffusion-weighted magnetic resonance images. Flow voids also surrounded the tumor on T2-weighted imaging, and intense contrast enhancement was observed in the early phase on dynamic contrast-enhanced T1-weighted imaging. These magnetic resonance imaging features could be useful for an accurate diagnosis for extramammary Paget's disease with an atypical gross form. Furthermore, they could serve as an indication for the discrimination from coexisting other skin disease such as condyloma acuminatum.