Identification of quinolinyl-containing dual soluble epoxide hydrolase/fatty acid amide hydrolase inhibitors with moderate potency towards acetylcholinesterase

Results in Chemistry 2026 Open access

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Authors: Michael Gonzalez, Ryan West, Amanda Tsang, Olivia Ocampo, Paula K. Hudson, Stevan Pecic
DOI: 10.1016/j.rechem.2026.103159
Cited by: 1
References: 59

Abstract

revealed key interactions with FAAH and sEH but limited interactions with AChE, suggesting directions for future structural modifications that could improve potency and selectivity.

Fields of Study & Subjects

Eicosanoids and Hypertension Pharmacology Enzyme function and inhibition Cholinesterase and Neurodegenerative Diseases

Publication details

Journal / source
Results in Chemistry
Publisher
Elsevier BV
Volume
23
Pages
103159–103159
Publication date
21 February 2026
Language
EN