Three components synthesis of tetracyclic fused Scafold of Pyrazolopyrimidobenzosultam derivatives
Abstract
A feasible and effective method for synthesising Pyrazolopyrimidobenzosultam by a three-component one-pot reaction comprising N-methyl 1,2-benzothiazinone 1,1-dioxide, a suitable benzaldehyde, and 5-amino pyrazole with KOH has been presented. This method was implemented successfully without the use of heavy metals and had positive yields. Development of a new heterocyclic structure incorporating pyrazole, dihydropyridine and sultam scaffolds through Michael addition, cyclisation, and condensation processes.
Fields of Study & Subjects
Multicomponent Synthesis of Heterocycles
Synthesis and Characterization of Heterocyclic Compounds
Synthesis of heterocyclic compounds
Publication details
- Journal / source
- Results in Chemistry
- Volume
- 26
- Pages
- 103194–103194
- Publication date
- 3 March 2026
- Language
- EN