N,N-Dimethylacetamide Exposure–Induced Acute Liver Failure
Abstract
This study aimed to share the case caused by N,N-Dimethylacetamide (DMAC) exposure. We report a 30-year-old man who died from DMAC exposure-induced acute liver failure after working in the cutting and cleansing of hollow fibre membranes for 5 days. While he was exposed to low-level DMAC by inhalation as the measurement of periodic working environment monitoring, considering his working method, considerable DMAC exposure via dermal absorption was suspected. Therefore, short-term, short-latency DMAC exposure via dermal absorption can cause fatal acute liver failure owing to idiosyncratic reactions.
Fields of Study & Subjects
Carcinogens and Genotoxicity Assessment
Contact Dermatitis and Allergies
Occupational exposure and asthma
Publication details
- Journal / source
- Safety and Health at Work
- Publisher
- Elsevier BV
- Volume
- 17
- Issue
- 3
- Pages
- 426-429
- Publication date
- 1 April 2026
- Language
- EN