Diffusion tensor imaging (DTI) combined with diffusion tensor tractography (DTT) in the brain function and volumetric imaging in children with autism

OBJECTIVE: To explore the application value of DTI combined with DTT in brain function and volume in children with autism. METHODS: A total of 616 children with autism diagnosed from January 2020 to December 2022 (ASD group) and 91 healthy children with age and gender matching (control group) were included in the study. All subjects underwent DTI and DTT examinations. The DTI-DTT examination was conducted to analyze the Fractional Anisotropy (FA) values of key brain regions such as the corpus callosum and internal capsule, and the correlation and diagnostic efficacy were analyzed with the scores of the Autism Behavior Checklist (ABC). RESULTS: The total scores of ABC and each factor in the ASD group were significantly higher than those in the control group (p