Obstructive sleep apnea and echocardiographic indicators of elevated pulmonary hypertension probability after pulmonary endarterectomy in chronic thromboembolic pulmonary hypertension

We previously demonstrated that 80% of patients with chronic thromboembolic pulmonary hypertension (CTEPH) exhibit sleep-related breathing disorders (SBDs), primarily obstructive sleep apnea (OSA), followed by isolated sleep-related hypoxemia (ISRH). In this follow-up study, we aimed to assess the distribution of SBDs and predictors of echocardiography-based residual pulmonary hypertension (PH) risk after pulmonary endarterectomy (PEA) in the same cohort. Overnight polysomnography and echocardiography were performed in 24 CTEPH patients approximately 112±65 days after PEA. residual PH risk was defined as peak tricuspid regurgitation velocity (TRV) >2.8 m/s and systolic pulmonary artery pressure (SPAP) ≥ 30 mmHg. In the overall cohort, PEA significantly reduced TRV (from 3.7±0.9 to 2.5±0.9 m/s, p