Identifying Subsets of Patients with Non-immunogenic Gastrointestinal Cancers for Checkpoint Immunotherapy

Surgical Oncology Clinics of North America 2026 Open access

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Authors: Cindy M. Pabon, Piyush Kumar-Sharma, Benjamin Oren Spieler, Daniel Tuerff, Jashodeep Datta, Peter J. Hosein
DOI: 10.1016/j.soc.2025.10.008
Cited by: 0
References: 115

Abstract

Efforts to expand immunotherapy benefit in gastrointestinal cancers focus on identifying subsets that may be more responsive to checkpoint blockade, developing combination strategies to overcome immunotherapy resistance, and leveraging the tumor microenvironment to enhance immune responsiveness in traditionally non-immunogenic malignancies.

Fields of Study & Subjects

Cancer Immunotherapy and Biomarkers Colorectal Cancer Treatments and Studies Immunotherapy and Immune Responses

Publication details

Journal / source
Surgical Oncology Clinics of North America
Volume
35
Issue
2
Pages
347–365
Publication date
14 January 2026
Language
EN