Directional replicability: When can the factor of two be omitted
Abstract
Directional replicability addresses the question of whether an effect studied across n independent studies is present with the same direction in at least r of them, for r ≥ 2. When the expected direction of the effect is not specified in advance, the state of the art recommends assessing replicability separately by combining one-sided p-values for both directions (left and right), and then doubling the smaller of the two resulting combined p-values to account for multiple testing. In this work, we show that this multiplicative correction is not always necessary, and give conditions under which it can be safely omitted.
Fields of Study & Subjects
Meta-analysis and systematic reviews
Statistical Methods in Clinical Trials
Probability and Statistical Research
Publication details
- Journal / source
- Statistics & Probability Letters
- Volume
- 233
- Pages
- 110662–110662
- Publication date
- 30 January 2026
- Language
- EN