Minimizing far-extending chromatin perturbation in genome editing preserves stem cell identity

Cell stem cell 2026

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Authors: Ming Zhu, Junsong Yuan, Qiuchen Meng, Jiawei Yu, Xiaoqing Xu, Mingyue Xu, Xiaoyu Ren, Yanyan Hu, Guoan Wei, Zeran Jia, Guohua Yuan, Lu Zang
+13 more Shaorui Liu, Yuanyuan Yang, Yuan Zheng, Jiacheng Wang, Tingting Cong, Wei Xie, Xun Lan, Le Cong, Tianhua Ma, Sheng Ding, Weixiang Guo, Xuegong Zhang, Yinqing Li
DOI: 10.1016/j.stem.2026.01.015
Cited by: 3
References: 117

Fields of Study & Subjects

CRISPR and Genetic Engineering RNA regulation and disease Chromosomal and Genetic Variations

Publication details

Journal / source
Cell stem cell
Publisher
Elsevier BV
Volume
33
Issue
3
Pages
470–486.e14
Publication date
24 February 2026
Language
EN