Recent advances in mechanochemical metal-catalyzed cross-coupling reactions

Tetrahedron Chem 2026 Open access

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Authors: Suman Yadav, Radovan Šebesta
DOI: 10.1016/j.tchem.2026.100158
Cited by: 2
References: 97

Abstract

Cross-coupling reactions are key chemical transformations allowing efficient construction of structurally diverse molecules. This review surveys recent progress in metal-catalyzed cross-coupling reactions conducted under mechanochemical conditions. In recent years, a variety of mechanochemical protocols have been developed that allow the realization of Suzuki-Miyaura, Heck, Sonogashira, Negishi cross-coupling, cross-electrophile couplings, and Buchwald-Hartwig aminations.

Fields of Study & Subjects

Crystallography and molecular interactions Vanadium and Halogenation Chemistry Catalytic Cross-Coupling Reactions

Publication details

Journal / source
Tetrahedron Chem
Publisher
Elsevier BV
Volume
18
Pages
100158–100158
Publication date
28 March 2026
Language
EN