Machine learning for evolutionary genetics and molecular evolution

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Authors: Nicolas Svetec, UnJin Lee, Li Zhao
Cited by: 2
References: 91

Abstract

Over the past decade, the rapid expansion of large-scale data and advances in computational power have allowed machine learning (ML), especially deep learning, to reshape many areas of biological research. Evolutionary genetics and molecular evolution are also poised for a similar transformation. In this review, we discuss key advances and ongoing challenges in applying ML to the study of genetics and evolution, and we highlight the potential of artificial intelligence to connect genotype, phenotype, and evolutionary history.

Fields of Study & Subjects

Evolution and Genetic Dynamics Machine Learning in Bioinformatics Evolutionary Algorithms and Applications

Publication details

Journal / source
Trends in Genetics
Publisher
Elsevier BV
Volume
42
Issue
5
Pages
423–433
Publication date
24 March 2026
Language
EN