Silencing the noise with gene body methylation
Abstract
Gene body methylation (gbM) is a conserved plant epigenetic mark previously correlated with stable gene expression. Zastąpiło et al. now demonstrate that gbM actively suppresses interindividual transcriptional noise. Using mutants and epigenetic recombinant inbred lines, they establish a causal link between gbM and expression stability.
Fields of Study & Subjects
Epigenetics and DNA Methylation
Pluripotent Stem Cells Research
Genomics and Chromatin Dynamics
Publication details
- Journal / source
- Trends in Genetics
- Publisher
- Elsevier BV
- Volume
- 42
- Issue
- 6
- Pages
- 484–485
- Publication date
- 24 April 2026
- Language
- EN