Influenza epidemiology, treatment and prevention in Australian children: Trends from 6 years of PAEDS-FluCAN influenza surveillance (2019–2024)

Vaccine 2026 Open access

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Authors: Emily Rice, Allen C. Cheng, Phillip N. Britton, Jeremy Carr, Julia E. Clark, Nigel W. Crawford, Joshua R. Francis, Kristine K. Macartney, Helen S. Marshall, Nicholas J. Wood, Christopher C. Blyth
DOI: 10.1016/j.vaccine.2026.128592
Cited by: 1
References: 27

Abstract

BACKGROUND: Influenza remains an important cause of pediatric morbidity and mortality. Immunisation is critical to prevent hospitalisation and severe disease. The COVID-19 pandemic had far-reaching effects on influenza epidemiology and vaccine use. METHODS: Participants were recruited prospectively from sentinel hospital sites (2019-2024). Children hospitalised with an acute respiratory illness (ARI) and laboratory-confirmed influenza were considered cases whilst those testing negative were considered controls. Vaccine effectiveness was estimated from the adjusted odds ratio of vaccination in cases and controls. RESULTS: There were 8762 hospitalised influenza cases and 10,955 influenza-test-negative controls in children

Fields of Study & Subjects

Influenza Virus Research Studies Respiratory viral infections research Pneumonia and Respiratory Infections

Publication details

Journal / source
Vaccine
Publisher
Elsevier BV
Volume
82
Pages
128592–128592
Publication date
19 April 2026
Language
EN