From Genes to Infections: A Complex Case of Leaky SCID with Dual Opportunistic Infections Disseminated Tuberculosis and Renal Fungal Ball
Abstract
To report a rare and complex case of disseminated mycobacterial and fungal infections in a pediatric patient with leaky severe combined immunodeficiency (SCID) caused by a homozygous JAK3 mutation, and to highlight the diagnostic and therapeutic challenges in managing such immunodeficiencies in tuberculosis-endemic regions.
Fields of Study & Subjects
Immunodeficiency and Autoimmune Disorders
Tuberculosis Research and Epidemiology
Infectious Diseases and Tuberculosis
Publication details
- Journal / source
- World Allergy Organization Journal
- Volume
- 19
- Issue
- 2
- Pages
- 101298–101298
- Publication date
- 1 February 2026
- Language
- EN