Biologic Therapies in ENT: A Systematic Review of Efficacy, Safety, and Outcomes

World Allergy Organization Journal 2026 Open access

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Authors: Zainab Al Saloom, Zahraa Adel Mohamed, Esra M. Qadami, Alaa Q. Mandeel, Mahmood Alowainati
DOI: 10.1016/j.waojou.2026.101326
Cited by: 0

Abstract

Biologic therapies, including Omalizumab, Mepolizumab, and Dupilumab, offer a targeted approach for managing several conditions including Ear, Nose, and Throat (ENT) diseases like resistant cases of chronic rhinosinusitis with nasal polyps (CRSwNP), allergic rhinitis, and autoimmune inner ear disease. This systematic review evaluated the indications, efficacy, and safety of biologics in treating ENT conditions.

Fields of Study & Subjects

Sinusitis and nasal conditions Allergic Rhinitis and Sensitization Asthma and respiratory diseases

Publication details

Journal / source
World Allergy Organization Journal
Volume
19
Issue
2
Pages
101326–101326
Publication date
1 February 2026
Language
EN