Syndecan-1-targeted therapeutic antibody impairs macropinocytosis and elicits antitumor immunity in pancreatic cancer

Cell Reports Medicine 2026 Open access

Read full text
Authors: Zecheng Yang, Madelaine S. Theardy, Shuaitong Chen, Yongkun Wei, Mitsunobu Takeda, Yue Zeng, Xiaofei Wang, Jun Yao, Jennifer Li, Prapassorn Thirasastr, Jangho Park, Yangxi Zheng
+11 more Long Vien, Khalida M. Wani, Huamin Wang, Sisi Gao, Tim Heffernan, Lawrence N. Kwong, Ignacio I. Wistuba, Laura C. Bover, Giulio F. Draetta, Haoqiang Ying, Wantong Yao
DOI: 10.1016/j.xcrm.2026.102613
Cited by: 1
References: 45

Fields of Study & Subjects

Proteoglycans and glycosaminoglycans research Glycosylation and Glycoproteins Research Cell Adhesion Molecules Research

Publication details

Journal / source
Cell Reports Medicine
Publisher
Elsevier BV
Volume
7
Issue
2
Pages
102613–102613
Publication date
1 February 2026
Language
EN