Reprogramming T cell-myeloid crosstalk overcomes immune resistance in colorectal cancer

Cell Reports Medicine 2026 Open access

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Authors: Guillaume Mestrallet, Matthew Brown, Natalie Vaninov, Nam Woo Cho, Leandra Velazquez, Aparna Ananthanarayanan, Matthew Spitzer, Nicolas Vabret, Cansu Cimen Bozkus, Robert Samstein, Nina Bhardwaj
DOI: 10.1016/j.xcrm.2026.102786
Cited by: 3
References: 65

Abstract

T cells, while reducing immunosuppressive myeloid infiltration and T cell exhaustion, identifying key cellular programs that overcome immune escape in CRC.

Fields of Study & Subjects

CAR-T cell therapy research Immune cells in cancer Phagocytosis and Immune Regulation

Publication details

Journal / source
Cell Reports Medicine
Publisher
Elsevier BV
Volume
7
Issue
5
Pages
102786–102786
Publication date
1 May 2026
Language
EN