Uncovering diversity in the immunoglobulin heavy chain locus

Cell Genomics 2026 Open access

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Authors: Jill A. Hollenbach
DOI: 10.1016/j.xgen.2025.101134
Cited by: 0
References: 8

Abstract

The immunoglobulin heavy chain constant (IGHC) locus houses genetic determinates of antibody function and specificity. In this issue of Cell Genomics, Jana et al. use long-read sequencing to characterize extensive inter-individual diversity in the IGHC region across ancestrally diverse populations, highlighting potential functional consequences.

Fields of Study & Subjects

Monoclonal and Polyclonal Antibodies Research Genetic Associations and Epidemiology Genomics and Chromatin Dynamics

Publication details

Journal / source
Cell Genomics
Volume
6
Issue
1
Pages
101134–101134
Publication date
1 January 2026
Language
EN