A transferrin receptor-targeted α-L-fucosidase, JR-471, reduced core-fucosylated glycoasparagine in the brain and preserved motor function in a murine model of fucosidosis

Molecular Genetics and Metabolism 2026

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Authors: Tomomi Masuda, Eiji Yoden, Takashi Onouchi, Saki Fujiyama, Hidehiko Hashimoto, Kazuki Miyauchi, Hideto Morimoto, Tadao Shibasaki, Kohtaro Minami, Toru Hirato, Hiroyuki Sonoda, Keníchi Takahashi
DOI: 10.1016/j.ymgme.2025.109544
Cited by: 0

Fields of Study & Subjects

Lysosomal Storage Disorders Research Glycogen Storage Diseases and Myoclonus Metabolism and Genetic Disorders

Publication details

Journal / source
Molecular Genetics and Metabolism
Volume
147
Issue
2
Pages
109544–109544
Publication date
1 February 2026
Language
EN