Basic enables selection-free efficient knockin of large DNA in primary human T cells

Molecular Therapy 2026 Open access

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Authors: Kexin Wang, Xiaorui Li, Jin Li, Zhuoying Yu, Pan Li, Yuyang Xie, Jinxin Liu, Honglin Huang, Shanshan Zhang, Mengqiao Zhang, Wenju Ma, Fei Gao
+4 more Xuguang Du, Jianxun Wang, Mario R. Capecchi, S. Vincent Wu
DOI: 10.1016/j.ymthe.2025.12.064
Cited by: 0
References: 59

Fields of Study & Subjects

CAR-T cell therapy research Virus-based gene therapy research CRISPR and Genetic Engineering

Publication details

Journal / source
Molecular Therapy
Volume
34
Issue
4
Pages
2309–2323
Publication date
2 January 2026
Language
EN