T cell receptor gene therapy targeting KRAS G12V for advanced pancreatic cancer in a single-arm phase 1/2 clinical trial

Molecular Therapy 2026 Open access

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Authors: Xiongfei Xu, Haihui Gu, Zhanshan Cha, Bin Zhang, Shuai Yuan, Xiuwen Ding, Lei Gao, Suizhi Gao, Xinqian Wu, Lingyun Gu, Jianye Huang, Jianling Hao
+20 more Penghao Li, Yikai Li, Xiaochao Kang, Xiaohan Shi, Xiaoyi Yin, Huan Wang, Bo Li, Meilong Shi, Wei Jing, K Zheng, Chunhong Zheng, Yi-Ping Shih, Cong Wu, Chenggang Zheng, Baohua Qian, Gusheng Tang, Jianmin Yang, Shiwei Guo, Eric Tran, Gang Jin
DOI: 10.1016/j.ymthe.2026.03.012
Cited by: 2
References: 51

Fields of Study & Subjects

CAR-T cell therapy research Virus-based gene therapy research Pancreatic and Hepatic Oncology Research

Publication details

Journal / source
Molecular Therapy
Publisher
Elsevier BV
Volume
34
Issue
7
Pages
4001–4020
Publication date
11 March 2026
Language
EN