Savolitinib plus osimertinib versus chemotherapy for advanced, EGFR mutation-positive, MET-amplified non-small-cell lung cancer in China (SACHI): interim analysis of a multicentre, open-label, phase 3 randomised controlled trial

The Lancet 2026

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Authors: Shun Lu, Shun Lu, Nong Yang, Jie Wang, Nong Yang, Dongqing Lv, Lijuan Chen, Longhua Sun, Xingya Li, Longhua Sun, Yongfeng Yu, Bo Jin
+88 more Lin Yang, Yubiao Guo, Xu H, Tienan Yi, Aiping Zeng, Xiaorong Dong, Jianhua Chen, Ziping Wang, Hongrui Niu, Ying Cheng, Hongming Pan, Pengbo Deng, Hongming Pan, Xuhong Min, Jun Bai, Juan Li, Tongmei Zhang, Juan Li, Songhua Fan, Michael M. Shi, Tony Mok, Weiguo Su, Shun Lu, Shun Lu, Jie Wang, Jie Wang, Nong Yang, Dongqing Lv, Lijuan Chen, Lin Wu, Xingya Li, Longhua Sun, Haipeng Xu, Bo Jin, Lin Yang, Yubiao Guo, Xu H, Tienan Yi, Aiping Zeng, Xiaorong Dong, Jianhua Chen, Ziping Wang, Hongrui Niu, Ying Cheng, Pinhua Pan, Pengbo Deng, Hongming Pan, Xuhong Min, Jun Bai, Laiyu Liu, Tongmei Zhang, Juan Li, Songhua Fan, Michael M. Shi, Tony Mok, Weiguo Su, Feng Ye, Xianling Liu, Jianhua Shi, Jiwei Liu, Qisen Guo, Weihua Yang, Junfang Tang, Shundong Cang, Ou Jiang, Jian Fang, Guohua Yu, Lijun Wang, Xibin Zhuang, Zhigang Han, Yiping Zhang, Zhengbo Song, Baogang Liu, Buhai Wang, Jianying Zhou, Wei Gu, Hongcheng Wu, Zhiwei Lu, Yan Yang, Wen Dong, Xiuhua Fu, Youling Gong, Jinhuo Lai, Ping Sun, Yingying Du, Zhihua Liu, Diansheng Zhong, Kaihua Lu
DOI: 10.1016/s0140-6736(25)01811-2
Cited by: 25
References: 32

Fields of Study & Subjects

Lung Cancer Treatments and Mutations Fibroblast Growth Factor Research Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

Publication details

Journal / source
The Lancet
Publisher
Elsevier BV
Volume
407
Issue
10526
Pages
375–387
Publication date
1 January 2026
Language
EN