Tenecteplase versus standard medical treatment for basilar artery occlusion within 24 h (TRACE-5): a multicentre, prospective, randomised, open-label, blinded-endpoint, superiority, phase 3 trial

The Lancet 2026

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Authors: Yunyun Xiong, Fana Alemseged, Zhixin Cao, Lee H Schwamm, Si Zhang, Mark W Parsons, MJ Fisher, Yahui Hao, Aoming Jin, Jinfeng Yin, Yong Jiang, Fengyuan Che
+88 more Lihua Wang, Li Zhou, Hongguo Dai, Yutie Zhao, Chunmiao Duan, Shuangzhe Wu, Ganghua Feng, Lixia Zong, Wanxing Ye, Ziran Wang, Ziqi Xu, Hao Wang, Manjun Hao, Yujie Ma, Xia Meng, Hongxia Li, Zixiao Li, Yilong Wang, Yilong Wang, Liping Liu, Xingquan Zhao, Bruce C V Campbell, Bruce C V Campbell, Yongjun Wang, Yongjun Wang, Yunyun Xiong, Fana Alemseged, Zhixin Cao, Lee H Schwamm, Si Zhang, Mark W Parsons, Marc Fisher, Yahui Hao, Aoming Jin, Jinfeng Yin, Yong Jiang, Fengyuan Che, Lihua Wang, Li Zhou, Hongguo Dai, Yutie Zhao, Chunmiao Duan, Shuangzhe Wu, Ganghua Feng, Lixia Zong, Wanxing Ye, Ziran Wang, Ziqi Xu, Hao Wang, Manjun Hao, Yujie Ma, Xia Meng, Liping Liu, Zixiao Li, Yilong Wang, Yongjun Wang, Liping Liu, Xiaoxi Yao, Bruce C V Campbell, Bruce C V Campbell, Yongjun Wang, Yongjun Wang, Yuzhang Bei, Xiaoxi Yao, Xiangchen Zhou, Feng Ryan Wang, Hongling Guo, Jinglin Yuan, Junfeng Zhao, Yanqiu Du, Ying Liu, Jinzhao He, Tingting Zhang, Xing Fang, Yanbo Huang, Zhaolong Peng, Di Zhong, Jianxin Xu, S S Wu, Tao Zhang, Xuying He, Haitao Wang, Guosheng Han, Weiying Di, Muhui Lin, Qianqian Qiu, Wei Zhang, Xiaomin Xiong
DOI: 10.1016/s0140-6736(25)02633-9
Cited by: 11
References: 29

Fields of Study & Subjects

Retinal and Optic Conditions Acute Ischemic Stroke Management Peripheral Artery Disease Management

Publication details

Journal / source
The Lancet
Publisher
Elsevier BV
Volume
407
Issue
10530
Pages
763–772
Publication date
1 February 2026
Language
EN