Perioperative serplulimab with neoadjuvant chemotherapy versus perioperative chemotherapy in PD-L1-positive gastric cancer (ASTRUM-006): a randomised, double-blind, multicentre, phase 3 study

The Lancet 2026

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Authors: Lin Shen, Xiaotian Zhang, Ke Ji, Linzhi Lu, Quan Wang, Quanlin Guan, Yan Su, Yanbing Zhou, Yan Yang, Zhibin Huo, Jun You, Yi Ba
+63 more Yingjiang Ye, Ye Chen, Shubin Wang, Guoqing Lv, Jingdong Zhang, Xuhui Hu, Futang Yang, Haoyu Yu, Jing Li, Qingyu Wang, Jun Zhu, Jiafu Ji, Yong Li, Zekuan Xu, Xiaogang Bi, Zhiqiang Zhu, Gang Wang, Lisong Teng, Jun Liang, Congqiao Jiang, Meili Sun, Chunkang Yang, Yanhong Deng, Kaixiong Tao, Guoping Sun, Yun Tang, Xiaolei Chen, Suxia Luo, Yingwei Xue, Ying Yuan, Dan Wu, Jiankun Hu, Xianli Yin, Zhenning Wang, Funan Liu, Zhen Li, 牟一平, Wensheng Pan, Xiaorong Li, Peiguo Cao, Shaojun Chen, Jingzhang Li, Baoshan Cao, 薄元恺, Changming Huang, 王晓强, 毕铁男, Nanrong Yu, Xiaojun Yang, Yunbo Tan, Yongchang Zhang, 王海江, Guoquan Tao, Hongming Pan, Zhigang Jie, Junhe Li, Xianglin Yuan, Zhixin Cao, zihua Chen, Jie Ge, Tao You, Ziwei Wang, Bo Shen
DOI: 10.1016/s0140-6736(26)00974-8
Cited by: 8
References: 34

Fields of Study & Subjects

Gastric Cancer Management and Outcomes Cholangiocarcinoma and Gallbladder Cancer Studies Cancer Immunotherapy and Biomarkers

Publication details

Journal / source
The Lancet
Publisher
Elsevier BV
Volume
407
Issue
10547
Pages
2542–2553
Publication date
1 June 2026
Language
EN