Efficacy and safety of inclisiran in adolescents with heterozygous familial hypercholesterolaemia (ORION-16): a two-part, randomised, multicentre clinical trial

The Lancet Diabetes & Endocrinology 2026 Open access

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Authors: Albert Wiegman, Amy L Peterson, Eric Bruckert, Joep C. Defesche, Anja Schweizer, Jean Bergeron, María J Chueca, Jeanine E Roeters van Lennep, Raul D Santos, Karl Otfried Schwab, Anastasia Lesogor, Sijia Zhang
+1 more Robert A Hegele
DOI: 10.1016/s2213-8587(25)00351-1
Cited by: 5
References: 28

Fields of Study & Subjects

Lipoproteins and Cardiovascular Health Cholesterol and Lipid Metabolism Diabetes Cardiovascular Risks and Lipoproteins

Publication details

Journal / source
The Lancet Diabetes & Endocrinology
Publisher
Elsevier BV
Volume
14
Issue
3
Pages
233–242
Publication date
27 January 2026
Language
EN