From overlooked to just right: putting the focus on metronidazole infusion timing for colorectal surgical prophylaxis

Antimicrobial Stewardship & Healthcare Epidemiology 2026 Open access

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Authors: Peter Oakes, Lindsay E Donohue, Sunny S. Chiao, Susan Ketcham, Traci L. Hedrick, Rachele Olivier, Amy J. Mathers
DOI: 10.1017/ash.2025.10260
Cited by: 0
References: 7

Abstract

Preoperative prophylaxis efficacy depends on antibiotic infusion completion before incision. In our colorectal program, metronidazole often wasn't completed on time, in contrast to cefazolin. A multidisciplinary effort standardized its administration timing, improving infusion completion rates. We evaluated the impact of this intervention on surgical site infections in colorectal surgery.

Fields of Study & Subjects

Surgical site infection prevention Nosocomial Infections in ICU Colorectal Cancer Surgical Treatments

Publication details

Journal / source
Antimicrobial Stewardship & Healthcare Epidemiology
Volume
6
Issue
1
Pages
e13–e13
Publication date
1 January 2026
Language
EN