Associations between suppressive antibiotic therapy, treatment failure, and side effects among young, immunocompetent veterans with prosthetic joint infection who undergo debridement, antibiotics, and implant retention

Antimicrobial Stewardship & Healthcare Epidemiology 2026 Open access

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Authors: Marin Leigh Schweizer, Rajeshwari Nair, Kelly Richardson Miell, James Merchant, Brice F. Beck, Bruce Alexander, Daniel Y. Suh, Hiroyuki Suzuki, Aaron Joseph Tande, Mireia Puig‐Asensio, Kimberly Dukes, Julia E. Friberg Walhof
+4 more Andrew J. Pugely, Ambar Haleem, Michael J. Scolarici, Poorani Sekar
DOI: 10.1017/ash.2025.10273
Cited by: 0
References: 22

Abstract

Objective: Suppressive antibiotic therapy (SAT) is used to prevent recurrent prosthetic joint infections (PJI) among patients who undergo debridement, antibiotics, and implant retention (DAIR). We aimed to assess SAT outcomes among younger, immunocompetent patients. Design: Retrospective cohort study. Patients: Immunocompetent patients

Fields of Study & Subjects

Orthopedic Infections and Treatments Infective Endocarditis Diagnosis and Management Infectious Diseases and Tuberculosis

Publication details

Journal / source
Antimicrobial Stewardship & Healthcare Epidemiology
Volume
6
Issue
1
Pages
e52–e52
Publication date
1 January 2026
Language
EN