Leishmaniasis vaccine research: current status and new directions
Abstract
Leishmaniasis is a neglected parasitic disease responsible for significant morbidity and mortality. Currently, there is no vaccine approved for clinical use. Therefore, controlling infections in infected individuals depends on interventions to prevent infected female sand flies from biting humans, treatment of clinical infections or alternative treatment methods. This review focuses on the types of vaccine developed to control leishmaniasis and which vaccines have made it through to clinical trials. It also discusses the role CRISPR technology may play in improving vaccine candidates design.
Fields of Study & Subjects
Research on Leishmaniasis Studies
Parasitic Diseases Research and Treatment
Trypanosoma species research and implications
Publication details
- Journal / source
- Parasitology
- Publisher
- Cambridge University Press (CUP)
- Volume
- 153
- Issue
- 3
- Pages
- 366–377
- Publication date
- 7 January 2026
- Language
- EN