The role of negative affectivity in the developmental pathway linking perinatal complications to behavioral and emotional problems in children

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Authors: Xiaoye Xu, Lauren C. Shuffrey, Theresa M. Bastain, Chang Liu, Rosalind J. Wright, Michelle Bosquet Enlow, Alexis Hernandez, Jody M. Ganiban, Sara S. Nozadi, Amy E. Margolis, Amy J. Elliott, Santiago Morales
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References: 80

Abstract

Abstract Although temperamental negative affectivity has been identified as a developmental mechanism mediating the link between perinatal risk and internalizing problems in early childhood, its role in predicting broader behavioral and emotional problems across childhood remains understudied. We examined the longitudinal relations among perinatal complications (i.e., prenatal maternal depression and cardiometabolic complications, preterm birth, and low birth weight), children’s negative affectivity ( M age = 2.76; SD = 2.32; range = 0.24–12.46 years), and children’s internalizing, externalizing, and total problems ( M age = 5.12; SD = 2.63; range = 1.50–16.85 years) in the Environmental influences on Child Health Outcomes (ECHO) program ( N = 3070; 47% females). Results support child negative affectivity as a mechanism in the developmental pathway linking perinatal maternal depressive symptoms and preterm birth to future emotional and behavioral problems, underscoring the importance of early prevention and intervention efforts to promote psychological well-being of at-risk children.

Fields of Study & Subjects

Maternal Mental Health During Pregnancy and Postpartum Child and Adolescent Psychosocial and Emotional Development Infant Development and Preterm Care

Publication details

Journal / source
Development and Psychopathology
Volume
38
Issue
3
Pages
1322–1332
Publication date
16 February 2026
Language
EN