Ultrarapid Collection of High-Concentration Viral Samples from Small-Volume Exhaled Breath for Respiratory Virus Surveillance

Analytical Chemistry 2026

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Authors: Weihao Li, Han Gao, Mengqing Cheng, Manman Lv, Yemin Han, Haotian Yu, Weiming Lin, Yan Huang, Qiang Zhang, Dianhuai Meng, Tian Wen, Z. C. Lu
+1 more Liu Qk
DOI: 10.1021/acs.analchem.5c06572
Cited by: 4
References: 41

Abstract

Rapid and sensitive detection of airborne respiratory viruses from exhaled breath is essential for early diagnosis and outbreak control, yet current strategies suffer from low capture efficiency and sample dilution. Here, we present a fully automated, noninvasive Phase-change Drywall Cyclone Sampler (PDC-sampler), which integrates phase-change condensation with a CFD-optimized cyclone gas-liquid separator. This design rapidly condenses viral aerosols─particularly those

Fields of Study & Subjects

Advanced Chemical Sensor Technologies Respiratory viral infections research SARS-CoV-2 detection and testing

Publication details

Journal / source
Analytical Chemistry
Publisher
American Chemical Society (ACS)
Volume
98
Issue
10
Pages
7330–7341
Publication date
3 March 2026
Language
EN