An All-in-Tip Accelerated Proteomics Platform for Large-Scale Cancer Screening

Analytical Chemistry 2026

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Authors: Yating Wang, Yinbing Zhao, Ziheng Qi, Yang St, Weikang Shu, Yingying Lin, Yanhu Wang, Xiaonan Chen, Bin Li, Jiaxin Hou, Fanhe Yu, Xiaohui Liu
+2 more Lin Huang, Jingjing Wan
DOI: 10.1021/acs.analchem.5c06612
Cited by: 1
References: 42

Abstract

Large-scale plasma proteomics studies advance the human proteome atlas mapping and precision medicine, but face inefficiencies in sample processing. Here, we developed a fully automated, room-temperature All-in-Tip platform, enabling deep proteome profiling (>3000 protein groups per batch), high throughput (>4600 samples per day for sample preparation), and low cost (

Fields of Study & Subjects

Advanced Proteomics Techniques and Applications Advanced Biosensing Techniques and Applications vaccines and immunoinformatics approaches

Publication details

Journal / source
Analytical Chemistry
Publisher
American Chemical Society (ACS)
Volume
98
Issue
5
Pages
4050–4064
Publication date
29 January 2026
Language
EN