Automatic Coregistration of High-Resolution MALDI-MSI and Raman Imaging Applied to Cardiac Tissue of Fabry Disease Mouse Models

Analytical Chemistry 2026 Open access

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Authors: Johann Dierks, Eike Ulrich Brockmann, Anahi-Paula Arias-Loza, Thomas Bocklitz, P N Nordbeck, Kristina Lorenz, Elena Tolstik, Sven Heiles
DOI: 10.1021/acs.analchem.5c07622
Cited by: 1
References: 72

Abstract

Understanding early molecular changes in biological tissues is crucial for diagnosing pathological and genetic diseases and for elucidating their underlying mechanisms. However, localized molecular alterations of low-molecular-weight compounds (

Fields of Study & Subjects

Spectroscopy Techniques in Biomedical and Chemical Research Spectroscopy and Chemometric Analyses Mass Spectrometry Techniques and Applications

Publication details

Journal / source
Analytical Chemistry
Publisher
American Chemical Society (ACS)
Volume
98
Issue
28
Pages
20725–20737
Publication date
4 June 2026
Language
EN