Real-Time Visualization of Turbulent Micromixing in a T-Mixer: Submillisecond Homogenization Revealed by Chemiluminescence

Analytical Chemistry 2026 Open access

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Authors: Yuki Ishii, Tomohiro Ogawa, Ken Onda, Hiromichi V. Miyagishi, Yosuke Ashikari, Aiichiro Nagaki, Shusaku Asano, Kiyoshi Miyata
DOI: 10.1021/acs.analchem.6c00988
Cited by: 1
References: 58

Abstract

, indicating that turbulent stretching-dominated homogenization drives such quick micromixing even in the large-diameter T-mixer used in flow chemistry. By experimentally defining mixing time through direct observation of homogenization, without invoking reaction models or assumed micromixing parameters, this work establishes a general framework for designing mixers and reaction lengths for better utilization of short-lived intermediates and high-throughput flow chemistry.

Fields of Study & Subjects

Innovative Microfluidic and Catalytic Techniques Innovation Microfluidic and Capillary Electrophoresis Applications Microfluidic and Bio-sensing Technologies

Publication details

Journal / source
Analytical Chemistry
Publisher
American Chemical Society (ACS)
Volume
98
Issue
24
Pages
17928–17936
Publication date
8 June 2026
Language
EN