IGF2R-Targeted Alpha Therapy of Osteosarcoma Enabled by Conjugated [ 225 Ac]Ac-Macropa-PEG 4 -IF3

Bioconjugate Chemistry 2026

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Authors: Syed Qaiser Shah, Ralph Santos‐Oliveira, Derya Ilem-Ozdemir, Madeeha Shabnam

DOI: 10.1021/acs.bioconjchem.6c00125

Cited by: 1

References: 34

Abstract

-IF3 is a translational orphan alpha therapeutic for osteosarcoma with excellent radiochemical stability and potency and low off-target toxicity.

Radiopharmaceutical Chemistry and Applications Cancer Hypoxia and Metabolism Neuroblastoma Research and Treatments

References 34