Protein Amyloid and Synthetic Polymer Self-Assemblies: Similar Challenges for Their Preparation Associated with Shared Properties
Abstract
This publication constitutes a comparison of two apparently different communities, namely, synthetic polymer self-assemblies and amyloid aggregates, to cross-fertilize each other. The starting point is shared recognized issues in the reproducibility of the fabrication of the aggregates for each community. Based on this, this publication compares the underlying mechanistic principles of self-assembly, the methods for the preparation of assemblies, and the techniques used for their characterization. This highlights some common practices, while also revealing notable differences. Interestingly, some techniques may be used by both communities but with different perspectives and aims, whereas others are preferably employed by one community. The article finally suggests possible cross-advice for each one.
Fields of Study & Subjects
Supramolecular Self-Assembly in Materials
Alzheimer's disease research and treatments
Pickering emulsions and particle stabilization
Publication details
- Journal / source
- Biomacromolecules
- Publisher
- American Chemical Society (ACS)
- Volume
- 27
- Issue
- 2
- Pages
- 983–1007
- Publication date
- 19 January 2026
- Language
- EN