Biofilm- and Spore-Disruptive Star-Shaped Poly( l -lysine)/Hyaluronic Acid Microgels for Targeted Oral Therapy of Clostridioides difficile Infection

Biomacromolecules 2026 Open access

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Authors: I Shiuan Lin, C Y Chou, Yu‐Fang Chen, Ting-Yen Wang, Jing-Ting Lin, Ching‐Chi Lee, Jenn‐Wei Chen, Jeng‐Shiung Jan, Yuan‐Pin Hung
DOI: 10.1021/acs.biomac.5c02037
Cited by: 1
References: 61

Abstract

microgels as a microbiota-sparing therapeutic that targets multiple stages of CDI pathogenesis─including spores and biofilms─and demonstrate their potential for clinical translation.

Fields of Study & Subjects

Clostridium difficile and Clostridium perfringens research Bacteriophages and microbial interactions Nosocomial Infections in ICU

Publication details

Journal / source
Biomacromolecules
Publisher
American Chemical Society (ACS)
Volume
27
Issue
5
Pages
3019–3032
Publication date
22 April 2026
Language
EN