Visible–NIR Photodynamic and Photothermal Mono- and Bis-Rhodium(I) Complexes of a Pyrrole-Appended N-Confused Porphyrin

Inorganic Chemistry 2026

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Authors: Linxue Sang, Masatoshi Ishida, Yeting Wang, Yeting Wang, Feng Chen, Ru Feng, Jianming Pan, Yue Wang, Yue Wang
DOI: 10.1021/acs.inorgchem.5c05734
Cited by: 1
References: 29

Abstract

Pyrrole appending converts the peripheral site of an N-confused porphyrin into a robust monoanionic N, N chelate, enabling stable mono- and bis-Rh(I) complexes with square-planar Rh–N 2 (CO) 2 environments. Both complexes show broad visible–NIR absorption and dual photodynamic–photothermal activity. Mono-Rh(I) 3-Rh exhibits higher singlet-oxygen yields under green and 808 nm excitation, whereas bis-Rh(I) 3-Rh 2 displays superior photothermal efficiency. Computations reveal ligand-centered excitations in 3-Rh and enhanced metal–ligand mixing in 3-Rh 2, explaining their distinct energy-dissipation pathways.

Fields of Study & Subjects

Porphyrin and Phthalocyanine Chemistry Photodynamic Therapy Research Studies Nanoplatforms for cancer theranostics

Publication details

Journal / source
Inorganic Chemistry
Publisher
American Chemical Society (ACS)
Volume
65
Issue
3
Pages
2083–2091
Publication date
12 January 2026
Language
EN