Dual-Action NSAID-Gold(I) Alkynyl Hybrids for Synergistic Anti-Inflammatory and Anticancer Therapy of Colorectal Cancer

Inorganic Chemistry 2026 Open access

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Authors: Javier Sáez, Luis Vicente Herrera-Marcos, María Jesús Rodríguez-Yoldi, M. Concepción Gimeno, Elena Cerrada
DOI: 10.1021/acs.inorgchem.5c05908
Cited by: 4
References: 83

Abstract

transcription, highlighting a post-transcriptional anti-inflammatory action. These results support NSAID-derived alkynyl gold(I) complexes as promising multitarget agents for colorectal cancer intervention, combining disruption and COX-2 modulation.

Fields of Study & Subjects

Ferrocene Chemistry and Applications Metal complexes synthesis and properties Click Chemistry and Applications

Publication details

Journal / source
Inorganic Chemistry
Publisher
American Chemical Society (ACS)
Volume
65
Issue
13
Pages
7210–7223
Publication date
27 March 2026
Language
EN