Construction of a 19-Metal Cd(II)–Eu(III) Nanocluster for Visual and Real-Time Detection of Biopterin (a Cancer Marker) through Smartphone Scanning
Abstract
A 19-metal Cd(II)–Eu(III) nanocluster ( 1, sizes: 1.6 nm × 1.6 nm × 2.4 nm) was constructed for the luminescence detection of biopterin (Bio). Under the excitation at 380 nm, the enhancement of Eu(III) luminescence caused by Bio is described by I 615 nm = k × [Bio] + a, which is used to determine the concentrations of Bio in CH 3 CN, fetal calf serum, and urine with high sensitivity and selectivity. Prepared test strips of 1 are used to qualitatively check Bio through the color change to red, and real-time quantitative analysis of Bio can be further achieved through smartphone scanning. The luminescence response time of 1 toward Bio is less than 5 s, and the limits of detection are from 0.11 to 0.22 nM (ppb level).
Fields of Study & Subjects
Nanocluster Synthesis and Applications
Advanced Nanomaterials in Catalysis
Carbon and Quantum Dots Applications
Publication details
- Journal / source
- Inorganic Chemistry
- Publisher
- American Chemical Society (ACS)
- Volume
- 65
- Issue
- 19
- Pages
- 10526–10532
- Publication date
- 6 May 2026
- Language
- EN