Metal Organic Framework-Based Biosensors for Healthcare and Agricultural Applications
Abstract
Metal-organic frameworks (MOFs), with tunable structures, high porosity, and catalytic activity, are promising platforms for next-generation biosensors. MOF-based nanozymes (MOFzymes) and enzyme-MOF composites combine biological specificity with synthetic robustness, overcoming limitations of natural enzymes in complex environments. This review highlights recent advances in MOF-enabled biosensors for agricultural and healthcare applications, focusing on enzyme immobilization, nanozyme activity, and signal amplification strategies. MOFzymes enable low-cost, portable, and ultrasensitive detection of biomarkers, pathogens, pesticides, and environmental contaminants, although challenges remain in reproducibility, stability, selectivity in complex matrices, and scalable integration.
Fields of Study & Subjects
Advanced Nanomaterials in Catalysis
Carbon and Quantum Dots Applications
Advanced biosensing and bioanalysis techniques
Publication details
- Journal / source
- Journal of Agricultural and Food Chemistry
- Publisher
- American Chemical Society (ACS)
- Volume
- 74
- Issue
- 13
- Pages
- 10674–10688
- Publication date
- 25 March 2026
- Language
- EN