The Terpenoid Alkaloids of Colobognath Millipedes: Insights into Structural Diversity and Function

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Authors: Arden Hatch, Paul E. Marek, Emily E. Mevers
Cited by: 1
References: 60

Abstract

High Resolution Image Download MS PowerPoint Slide Colobognatha, a group of millipedes (Diplopoda) known for their unique biological traits ( e.g., brood care and sociality), is the only group among millipedes to produce terpenoid alkaloids. Before 2020, only four terpenoid alkaloids had been identified; however, recent studies have resulted in a surge of new chemical discoveries and research into their ecological and biochemical roles. In this review, we outline the social characteristics of Colobognatha, the chemical investigations of their defensive secretions, and the bioactivity of the terpenoid alkaloids with a particular emphasis on new findings. We conclude by summarizing gaps in the research on these chemicals and provide insights into future research directions.

Fields of Study & Subjects

Subterranean biodiversity and taxonomy Marine Sponges and Natural Products Crustacean biology and ecology

Publication details

Journal / source
Journal of Natural Products
Publisher
American Chemical Society (ACS)
Volume
89
Issue
1
Pages
29–38
Publication date
9 January 2026
Language
EN