Synthesis of Substituted Acridones and Pyranoacridines through Metal-Catalyzed C–H Bond Activation Strategy
Abstract
An efficient rhodium(III)-catalyzed oxidative bis-Heck-type olefination of acridone has been demonstrated using a C-H bond activation strategy. This reaction works very well with various acrylates and styrenes. Additionally, the synthesis of different pyranoacridines via a ruthenium(II)-catalyzed annulation protocol has also been achieved. The described protocols are quite compatible with various functional groups, and the desired products are isolated in moderate to good yields. Further, the preliminary photophysical properties of the synthesized pyranoacridines have also been studied.
Fields of Study & Subjects
Catalytic C–H Functionalization Methods
Sulfur-Based Synthesis Techniques
Catalytic Cross-Coupling Reactions
Publication details
- Journal / source
- The Journal of Organic Chemistry
- Publisher
- American Chemical Society (ACS)
- Volume
- 91
- Issue
- 2
- Pages
- 880–891
- Publication date
- 2 January 2026
- Language
- EN