One-Pot Synthesis of Thiocyanato-Containing Polycyclic Indolones through Photo-Induced Cascade Radical Cyclization/Thiocyanation/Oxidation of N -Acylindoles

The Journal of Organic Chemistry 2026

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Authors: Chukai Shao, Longcan Chen, Ruirui Hua, Xinzhe Zhao, Xiaowei Liu, Rui Tian, Hongquan Yin, Kaixiang Liu, Fu‐Xue Chen
DOI: 10.1021/acs.joc.5c02353
Cited by: 0
References: 65

Abstract

A photoinduced radical cascade cyclization/thiocyanation of N -acylindoles has been developed to obtain a series of thiocyanato-containing [1,3]oxazino[3,4- a ]indolones and indolo[2,1- b ]quinazolin-12(5 H )-ones. A wide scope of substrates has been tolerated in moderate to good yields under mild and metal-free conditions.

Fields of Study & Subjects

Radical Photochemical Reactions Synthesis of Indole Derivatives Sulfur-Based Synthesis Techniques

Publication details

Journal / source
The Journal of Organic Chemistry
Volume
91
Issue
5
Pages
2275–2283
Publication date
29 January 2026
Language
EN