Copper-Assisted Oxidative One-Pot Heterodifunctionalization of Cyclopentane-1,3-diones

The Journal of Organic Chemistry 2026 Open access

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Authors: Sapana Dubey, Sukanya Mandal, Rajarshee Sarkar, Biplab Koley, Shreya Roy, Krishna Prasad Bag, Subhrakanta Rout, Gokarneswar Sahoo, Damien Bonne, Tapas Das
DOI: 10.1021/acs.joc.5c02411
Cited by: 0
References: 27

Abstract

A novel one-pot oxidative heterodifunctionalization of saturated cyclopentane-1,3-dione has been developed via the aza-Michael addition of the NMe 2 radical generated from DMF solvent for the first time. This methodology offers a straightforward approach for the synthesis of aminated, halogenated, and chalcogenated cyclopentenone derivatives using copper halide as the halogen source and dichalcogenides as the chalcogen source.

Fields of Study & Subjects

Oxidative Organic Chemistry Reactions Radical Photochemical Reactions Sulfur-Based Synthesis Techniques

Publication details

Journal / source
The Journal of Organic Chemistry
Volume
91
Issue
5
Pages
1994–2003
Publication date
27 January 2026
Language
EN