Direct Synthesis of Triazaaryl Phosphine Sulfides from White Phosphorus
Abstract
A chlorine-free reaction was developed to synthesize triazaaryl phosphine sulfides and their analogues from white phosphorus (P 4 ). Mediated by diphenyl disulfide/diselenide and sodium hydride, the P−N bond was formed directly from P 4 with N-heteroaromatic substrates. This method features a one-pot process, mild conditions, and good substrate tolerance. A series of triazaaryl phosphine sulfides and their analogues were prepared with mild to excellent yields (58%−98%). In addition, the disulfide/diselenide media could be recycled.
Fields of Study & Subjects
Sulfur-Based Synthesis Techniques
Organophosphorus compounds synthesis
Synthesis and Reactivity of Sulfur-Containing Compounds
Publication details
- Journal / source
- The Journal of Organic Chemistry
- Publisher
- American Chemical Society (ACS)
- Volume
- 91
- Issue
- 6
- Pages
- 2345–2352
- Publication date
- 27 January 2026
- Language
- EN