Open Air Organophotocatalyzed Ring-Closing Cascade Trifluoromethylation of Dienes inside a Supramolecular Gel
Abstract
Mesoporous graphitic carbon nitride ( g -C 3 N 4 ) is an efficient heterogeneous photocatalyst. We report a redox-neutral trifluoromethylation of dienes using g -C 3 N 4 as a visible-light organophotocatalyst in a supramolecular gel platform under aerobic conditions. The gel medium suppresses oxygen diffusion, stabilizes intermediates, and enhances the photocatalytic efficiency, affording high yields. Using CF 3 SO 2 Na as the radical source, the reaction proceeds via radical addition and cyclization, producing trifluoromethylated saturated heterocycles with excellent chemo- and regioselectivity. Blue LED light (456 nm) drives oxidative and reductive electron transfer on g -C 3 N 4 . The method requires no metals, oxidants, or inert atmosphere, underscoring its sustainability.
Fields of Study & Subjects
Fluorine in Organic Chemistry
Radical Photochemical Reactions
Inorganic Fluorides and Related Compounds
Publication details
- Journal / source
- The Journal of Organic Chemistry
- Publisher
- American Chemical Society (ACS)
- Volume
- 91
- Issue
- 10
- Pages
- 3633–3640
- Publication date
- 2 March 2026
- Language
- EN