Mn(III)-Mediated Cascade Arylation/Cyclization of Ortho- (propargylamino) Aryl Isocyanides with Aryl Boronic Acids: Access to Tetracyclic Benzo[ b ]indeno[1,2- e ][1,4]diazepines

The Journal of Organic Chemistry 2026

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Authors: Kelin Yang, Puying Luo, Hong Yan, Liu Shuan Yang, Yiyuan Peng, Qiuping Ding
DOI: 10.1021/acs.joc.5c02589
Cited by: 0
References: 55

Abstract

A Mn(III)-promoted cascade arylation/cyclization of ortho -isocyano propargylanilines with aryl boronic acids has been developed. The protocol provides a novel and highly efficient access to construct two central rings (diazepine and cyclopenta-1,3-diene) of a tetracyclic product via the formation of three C–C bonds in one pot.

Fields of Study & Subjects

Catalytic C–H Functionalization Methods Catalytic Cross-Coupling Reactions Catalytic Alkyne Reactions

Publication details

Journal / source
The Journal of Organic Chemistry
Volume
91
Issue
3
Pages
1390–1395
Publication date
9 January 2026
Language
EN