Electrochemical Synthesis of α,α-Dichlorosulfoxides from Methyl Sulfoxides with Dichloromethane

The Journal of Organic Chemistry 2026

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Authors: Jiacheng Sun, Xuke Liu, Fengshi Sun, Xincheng Liu, Wenjing Yang, Chengcai Xia, Shu-Yong Song, Ying Zhao
DOI: 10.1021/acs.joc.5c02771
Cited by: 2
References: 28

Abstract

A novel electrochemical method for chlorination reactions which use methyl sulfoxides and dichloroethane to synthesize derivatives of α,α-dichlorosulfoxides has been developed. The reaction proceeds under mild conditions without transition metals and chemical oxidants in yields of up to 78%. In addition, mechanistic studies reveal that dichloromethane provides the chlorine source under electrolytic conditions. This strategy further expands the synthetic methods for gem -dichlorosulfoxides and provides a new approach to utilize dichloromethane as a chlorine source.

Fields of Study & Subjects

Vanadium and Halogenation Chemistry Oxidative Organic Chemistry Reactions Synthesis and Biological Evaluation

Publication details

Journal / source
The Journal of Organic Chemistry
Publisher
American Chemical Society (ACS)
Volume
91
Issue
4
Pages
1731–1736
Publication date
14 January 2026
Language
EN