Co(III)-Catalyzed C5–H Amination of Thiochromones with Anthranils

The Journal of Organic Chemistry 2026

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Authors: Seungyeon Lee, Keunju Park, Youngchang Kim, Anand Kumar, Jeonghyun Min, Amitava Rakshit, Joon-Ho Lee, Pargat Singh, In Su Kim
DOI: 10.1021/acs.joc.5c03162
Cited by: 0
References: 49

Abstract

The incorporation of a nitrogen unit into target molecules by generating nitrene species has become a hot topic in modern organic synthesis. In this study, we report a Co(III)-catalyzed C5-H amination of thiochromones with anthranils as aminating surrogates. The significance of this coupling reaction was demonstrated via a broad range of substrates and complete site selectivity. Moreover, post-transformations of synthesized products are described.

Fields of Study & Subjects

Synthesis and Catalytic Reactions Catalytic C–H Functionalization Methods Oxidative Organic Chemistry Reactions

Publication details

Journal / source
The Journal of Organic Chemistry
Volume
91
Issue
5
Pages
2248–2256
Publication date
28 January 2026
Language
EN